Early symptoms after a tick bite (3 to 30 days) include fever, muscle pain, joint pain, headache and a characteristic skin rash called erythema migrans. The rash occurs in most infected persons and can appear on any area of the body. The rash begins at the site of the tick bite slowly increases in size over a period of days. The rash usually is painless and does not itch. Sometimes the rash clears as it enlarges resulting in a target or “bull’s-eye” appearance.
If untreated, other symptoms can develop days to months after the tick bite. These include additional skin rashes, heart problems, nervous system disorders, and arthritis.